A histopathological study of prostate lesions in Awka, South-East Nigeria

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Chukwudi Onyeaghana Okani*, Chimezie Innocent Madubogwu,

Abstract

Introduction:


Diseases of the prostate gland are often associated with high morbidity and mortality if left undiagnosed in time. Common prostate diseases include: Nodular hyperplasia also known as Benign Prostatic Hyperplasia (BPH), cancers, prostatitis due to bacterial infections and parasitic infections of the prostate. Cancers of the prostate (CaP) are the most dreaded of all because the outcome is frequently grime in our society. Data show that CaP is the second most diagnosed cancer and amongst the leading causes of cancer deaths in males. We therefore, embarked on this study to determine the pattern of histopathological types of prostatic lesions seen in tertiary institution in South-East Nigeria.


Materials and Methods:


Surgical specimens received at the Department of Histopathology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH), Amaku-Awka, Anambra State, between January, 2013 and December, 2017 constituted the materials for the study.


 


 


 


 


 


Results:


Over the 5-year period, we processed a total of 252 prostatic tissue specimens. The age ranged between 46 years and 96 with a mean of 69.38 years ± 9.94. A total of 127 BPH (50.4%) was diagnosed, followed by 121 CaP (48.0%) and 4 (1.6%) cases were inadequate for diagnosis. The mean age of patients diagnosed with CaP was 71.21 years ±11.164, while that of patients diagnosed with BPH was 67.60 years±8.468. There was no significant age difference between men diagnosed with nodular hyperplasia and those diagnosed with cancers (p value = 0.844).


Conclusion: The BPH was the commonest disease of the prostate followed closely by Prostate cancer.

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